Please note that all times mentioned are CET (Central European Time)
The most notable and exciting work from abstracts submitted to the congress by early career scientists will be honored with an oral presentation in one of the Bright Sparks Workshops.These sessions will be part of the main program and will take place in real time. Presenters are expected to explain their work and answer questions from the audience in a live session. The awardees for the Biolegend Bright Sparks Awards will be chosen from those presentations.
Bright Sparks Workshop - BS.T1.01
| Cellular Immunology |
| Date & Time: September 2, 2021 / 11:30 – 12:45 |
| Chairs: TBA |
| Sander De Kivit, Netherlands The glycolysis intermediate lactate is essential for the suppressive function of human thymus-derived regulatory T cells |
| Katarzyna Nazimek, Poland The ability of extracellular vesicle-coating antibody light chains to bind antigenic peptides determines their immune suppressive activity |
| Maroua Ferhat, France A type 3 immunity (RORγt+) intrinsic PPARγ regulation contributes to diet-induced obesity |
| Rebecca Cornelis, Germany Maintenance of longlived memory plasma cells by contact to stromal cells through activation of PI3K/AKT and inactivation of FoxO1/3 prevents activation of caspase 3 |
| Sabrina Bianca Bennstein, Germany Characterisation of neonatal innate lymphoid subsets reveals a novel precursor able to generate NKG2A-KIR+ NK cells |
| Anna Pascual Reguant, Germany Phenotypic and spatial characteristics of human innate lymphoid cells revealed by highly multiplexed histology |
Bright Sparks Workshop - BS.T2.01
| Molecular Immunology |
| Date & Time: September 3, 2021 / 09:30 – 10:45 |
| Chairs: TBA |
| Kelsey O’Dowd, Canada Effect of MicroRNA gga-let-7f on Chicken Macrophage Functions in the Context of Antiviral Responses |
| Zhichao Ai, United Kingdom Distinct transcription factor networks control neutrophil-driven inflammation |
| Niamh M Troy, Australia Protection against severe lower respiratory infections in infants by Innate Immune Training: mechanism-of-action studies |
| Sofie Vandendriessche, Belgium Inhibition of drug-induced liver injury in mice using a positively-charged peptide that binds DNA |
| Lieve E.H. Van der Donk, Netherlands SARS-CoV-2-induced immunity depends on cytosolic sensors |
| Theresa Bierling, Germany The Role of Glucose Transporter Type 1 in Plasma Cells |
Bright Sparks Workshop - BS.T3.01
| Diseases and Immune Responses |
| Date & Time: September 3, 2021 / 14:30 – 15:45 |
| Chairs: TBA |
| Nicolas Riteau, France Protective role of the nucleic acid sensor STING in idiopathic pulmonary fibrosis |
| Sarah Case, Ireland Tumour Derived MicroRNA-21 Reprograms Macrophage Responses |
| Giulia Protti, Italy High-Throughput Single-Cell Analysis Revealed Transcriptional Response of Dendritic Cell Subsets During SARS-CoV-2 Infection |
| Andreas C Eberherr, Germany Rescue of STAT3 function in hyper-IgE syndrome using adenine base editing |
| Maud Heredia, Netherlands TIGIT expression differentiates regulatory from inflammatory non-classical Th1-like gut-homing effector CD4+ T cells in inflammatory bowel disease patients |
| Esin Alpdundar Bulut, Türkiye {Pediococcus pentosaceus} derived Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells |
Bright Sparks Workshop - BS.T4.01
| Vaccines and Immunotherapies |
| Date & Time: September 1, 2021 / 16:00 – 17:15 |
| Chairs: TBA |
| Banu Bayyurt Kocabas, United States TLR9 and STING ligands encapsulated into pH sensitive liposomes protected mice against melanoma tumor growth by elevating Th-1 immune response |
| Gunja Mishra, Netherlands PROTAC-mediated antigen degradation: A novel strategy to enhance CTL responses against cancer |
| Venugopal Gudipati, Austria Inefficient CAR-proximal signaling blunts antigen sensitivity |
| Laura Passeri, Italy Genetically engineered tolerogenic Dendritic Cells induce Ag-specific CD8+ T cell exhaustion and Ag-specific IL-10-produding T cells and modulate Type 1 Diabetes {in vivo} |
| Jelena Đokić, Serbia Inter-donor variability in dendritic cells capacity to respond to stimulation {in vitro} associates with donors gut microbiota composition |
| Florian Wimmers, United States The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination in humans |